Monday, February 24, 2014

Pitfalls of Skin Prick Testing in Food Allergy Diagnosis

Here's a paper on skin prick testing (SPT) and its pitfalls: http://www.ncbi.nlm.nih.gov/pubmed/20922509
 (be sure you're on BU network or VPN)

It explores the process of food allergy diagnoses and therapies in detail and concludes that the placebo-controlled oral food challenge is the gold standard in food allergy diagnosis. We should consider the merits of their arguments against our product and determine which food allergens are compatible with the skin prick test. Because our product works within the same theoretical framework as the skin prick test, we can evaluate our method with the same lens. However, we must also consider the improvements we make, such as the claim of increases specificity due to careful control of the application. Perhaps we can address their claims that current uses of SPT and serum food-specific IgE are insufficient without careful medical histories. Maybe we can knock some gold standards out of place!


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